Painkiller Jane premiered on Syfy on April 13, 2007. In the near future, with the world locked in an escalating battle against terrorism and beleaguered by social and economic unrest, an unlikely hero has emerged: Jane Vasco, a.k.a. Painkiller Jane. Once the DEA's top agent, Jane Vasco is formidable, both mentally and physically. As a child, her father nicknamed her Painkiller Jane, describing her ability to mentally push through even the most painful situations. But her strength is about to be tested. Jane is recruited by a covert government agency dedicated to containing and, if necessary, neutralizing the threat of "Neuros", individuals with superhuman neurological powers. No one knows what caused the aberrations that led to their enhanced abilities, which range from from telekinesis and telepathic suggestion to induced hallucinations. Seldom malicious, Neuros often can't control their powers. Consequently, they tend to leave a trail of death and destruction. To prevent a panic, the government has kept the discovery of Neuros a secret, assembling a covert unit to identify and contain Neuros.